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Long-term receiving ibuprofen and Alzheimer’s disease

November 9, 2008

Long-term receiving ibuprofen and other non-steroid drugs protects against Alzheimer’s disease

That conclusion came from researchers at Boston University in a study involving 250 thousand persons, said the journal Neurology.

Researchers under the leadership of Steven Vlad found that people who took ibuprofen for five years, more than 40% less likely to suffer senile dementia. Other NPVP have less effect – when they receive the risk of senile dementia has fallen on average by 24%, reported the scientists. Some funds from this group, in particular celexocib not have any impact on the development of dementia.

The protective effect of ibuprofen had previously been detected in animal studies, said Vlad. He noted that the admission of the drug led to a reduction of protein deposits in the brain characteristic of Alzheimer’s disease. New data confirm its role in preventing disease.

In previous studies, scientists have analyzed the relationship between the reception NPVP and dementia, but data collected by different authors, have been controversial. Vlad and his colleagues suggested that the discrepancy results linked to the uneven effects of various anti funds and were able to confirm this theory through his research.

Nevertheless, experts still can not recommend that patients use ibuprofen to prevent dementia. NPVP long-term use may cause serious side effects, including breach of kidney function and the formation of gastric ulcer, doctors warn.