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The device copes with severe asthma without drugs

November 9, 2009

The device copes with severe asthma without drugs
American scientists tested an experimental device that uses thermal energy to relieve bronchospasm in patients with severe bronchial asthma, intractable medical treatment.

As shown by one of the last stages of clinical trials, the use of Alair System – is the name of the device – a 32% reduced the incidence of severe asthma attacks and 84% of patients reduced the number of requests for emergency medical help.

In addition, patients who were treated by this device rarely took sick and miss school, and days free from asthma symptoms, they were more than those who received placebo.

The test results were presented at the 105-th international conference of the American Thoracic Society, held in San Diego (California, USA) from 15 to 20 May 2009

The principle of the Alair System is as follows: in the respiratory tract is introduced thin tube through which the high-frequency pulses are fed, heating and destroying the excess muscle tissue of the bronchioles, which prevents them from narrowing and obstruction. The procedure called bronchial thermoplastic and an outpatient.

“In bronchial asthma in the wall of the bronchioles, there are too many smooth muscle fibers, which promote the development of seizures, – explains study leader Dr. Mario Castro of the University. George Washington at St. Louis (Missouri, USA). – Our mission – to reduce their numbers” .

To participate in clinical trials, Dr. Castro and his colleagues have invited 297 patients with severe bronchial asthma from 30 hospitals in 6 countries. Two-thirds of all participants received 3 sessions of bronchial thermoplastics, the other represented the control group, in which during the procedure rf pulses were made.

Within a year after the procedure, scientists monitored the condition of patients. In 79% of subjects who passed the experimental treatment, the condition improved. According to Dr. Castro, improvement was noted in the control group, but its severity was not statistically significant. “This is a very important advance in the treatment of bronchial asthma, – said Dr. Castro, – to this day not much we can help these patients.

All patients enrolled in clinical trials, constantly taking a combination of drugs for inhalation of corticosteroids and b-agonists long-acting, but it did not give them much relief. Could also help immunomodulator omalizumab, intended for the treatment of allergic bronchial asthma, but not all patients the cause of asthma in allergy.

This fall, Alair System expects FDA approval. In Europe, bronchial thermoplastic already approved.

The lack of sunlight affects the severity of treatment of asthma

October 19, 2009

The lack of sunlight affects the severity of treatment of asthma
Levels of vitamin D in the body affect the severity of treatment of asthma , established doctors. Immunologists Harvard Medical School examined the concentration of vitamin D among 616 children diagnosed with asthma.

For each child tested for sensitivity to common allergens, but also examined serum vitamin D in the blood and lung function. Asthmatics who had low levels of vitamin A, significantly more likely to have been hospitalized with respiratory symptoms, often react to the most common markers of allergy, as dust mites, and had serious bouts of illness.

American immunologists believe that a walk in sunny weather, is essential for maintaining the health of asthmatics, since ultraviolet rays are an indispensable source of vitamin D. In sunlight, doctors recommend giving children with vitamin supplements, which will also preserve bone health, to prevent rickets and osteoporosis in adulthood. The complexity of obtaining vitamin D is that, unlike many other useful substances, it is mainly synthesized in the body, but not at the expense of consumption. Approximately 90% of vitamin D is formed in the body due to exposure to the sun, so even large amounts of products containing the substance can not fill the deficit, adding therapists.