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Statins reduce the risk of first or recurrent stroke

October 19, 2009

Statins reduce the risk of first or recurrent stroke
Results of large-scale meta-analysis indicate that the use of statins reduces the risk of both first and recurrent stroke.

Pierre Amarenco, and Julien Labreuche (Hemostasis, Bio-engineering, and Cardiovascular Remodeling Unit at INSERM in Paris, France) performed a meta-analysis study of stainov, it included 24 studies with a total of 165 792 participants.

In a meta-analysis showed that lowering LDL cholesterol by 1 mmol / L reduces the risk of stroke by 21.1%. Only one study examined the effectiveness of statins for secondary prevention of stroke, found that patients who took statins, the risk of recurrent stroke was 0.84.

Lancet Neurol 2009

Negative thoughts about aging impair memory

Negative thoughts about aging impair memory
If the age you are strongly associated with the development of multiple sclerosis, it is quite possible that in old age, you really will experience memory lapses.

Researchers at the University of North Carolina / United States / came to the conclusion that the negative thoughts about the signs of aging lead to a deterioration of memory. Experiments have shown that older people perform mental tasks and worse on memory tests if they are cultured in a negative stereotypes about aging. Memory functions are also affected, when retirees become hypochondriac about my age and believe that others are prejudiced against him for that reason. Affirmed that the negative stereotypes often affect memory in aged 60-70 years, and more on highly educated people.

As psychologists say, elderly people are often concerned about the opinion of others, especially in the working environment. Such obsessions reinforce negative stereotypes and not only lead to depression, excess stress and high anxiety, but also interfere with normal functioning of the brain. It was noticed that people who are on the contrary do not think about aging and do not pay attention to your own age, have a higher memory performance. In other words, be sure that aging does not disrupt your mental health, then the chances of a good memory in old age increase, say neuroscientists.

Lead harms the work of the brain

September 9, 2009

Lead harms the work of the brain
Exposure to lead results in cognitive problems and disrupts the brain. Researchers examined the health of nearly two thousand men working in factories for the production of batteries and lead acid batteries.

Emphasis on the analysis of neuro-cerebral activity, including psychomotor functions, spatial and executive, as well as learning skills and memory. Most workers had levels of lead in blood is much higher than the norm. Accumulation of lead in the body led to violations of the cognitive – the longer a person subjected to the influence of substances in the workplace, the worse the function of his brain, doctors have noticed.

Especially harmful lead affected the brain function of men older than 55 years, accelerating the aging of the brain and damaging the area, responsible for addressing specific cognitive tasks. However, according to American doctors, young men were also vulnerable to the adverse effects of lead. In addition to damage to the hippocampus and frontal cortex – the main area that controls memory and learning – lead also increases the risk of hypertension. Hypertension in turn also reduces cognitive abilities. Professions associated with the manufacture of semiconductors, ceramics, welding and soldering and includes some construction work, are at risk of negative effects of lead entering the body through the air and the skin, an expert of the University of Pittsburgh.

Found gene aging brain

Found gene aging brain
Canadian scientists from the University of Montreal and Maisonneuve-Rosemont Hospital, and their American colleagues at the Lawrence Berkeley National Laboratory made a big step towards opening the treatment of neurological diseases and develop drugs slow down the aging brain.

Experts have discovered a gene that controls the normal and pathological aging of neurons in the central nervous system – the gene Bmi1. Mutation of this gene greatly accelerates the process of dissolution of Neurosciences in the brain and loss of nerve cells in the eyes. Laboratory tests on mice showed that neurons in the retina and cerebral cortex functioning properly is at work found gene Bmi1. This gene also prevents the activation of p53 and the path accumulation of free radicals, leading to the advancement of brain disorders.

The main risk factor for diseases such as macular degeneration, Parkinson’s disease and Alzheimer’s disease, is old age. Many physicians seek to better understand the causes of these diseases, but few studies have focused on the consideration of the basic molecular mechanisms that control the aging of Neurosciences in the human body. Now geneticists have shown that Bmi1 is a direct regulator of cellular aging brain and retina due to its protective properties against harmful free radicals. Doctors hope that in the future be able to unravel the genome coding for neuronal damage.

The aging of the brain responsible sugar

The aging of the brain responsible sugar
Increased blood sugar levels, a normal sign of aging, affects the work of the hippocampus – the area of the brain, which is crucial for learning and memory. Scientists believe that it is too high blood glucose levels associated with cognitive dysfunction in old age.

It is assumed that the regulation of substances in the body will help prevent age-related decline in memory. At the same time, neurologists noticed that the excercises stabilize the concentration of glucose and, consequently, improve brain function.

Research at Columbia University / United States / showed that physical activity strengthens the part of the brain associated with aging by controlling blood sugar. Such conclusions were made after analysis of the functions of the hippocampus in 240 healthy people about 80 years. It is known that damage to the hippocampus develops Alzheimer’s disease and other cognitive problems. Doctors argue that maintaining optimal blood sugar levels and the implementation of regular physical exercise can effectively prevent a cognitive disorder and to support brain activity in old age.