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Found a cure for skin cancer

November 13, 2009

Found a cure for skin cancer
Scientists have developed a new drug that helps in the treatment of the most deadly types of skin cancer, including the most recent stages.

Malignant melanoma – one of the fastest growing types of cancer. Main reason for it – the solar radiation. According to the results of preliminary tests, the drug while still under development and which bears the name of PLX4032 (R7204), can provide a long life expectancy.

Pharmaceutical companies Roche and Plexxikon announced the results of their research at the annual convention of the American Society of Clinical Oncology. PLX4032 (R7204) finds and destroys tumor cells carry the mutation type BRAF, which is present in 60% of malignant melanomas. This can help not only reduce the number of malignant tumors, but also slow the spread of cancer.

Clinical trials

Currently, only 5% of people live more than two years after the appearance of metastases. In the first phase of a clinical study in 16 patients receiving the drug PLX4032 (R7204) was found to decrease proliferation of tumor cells by at least 30%.

On average, these patients have stopped the cancer cells to spread about half a year, while more than half of the tumors were markedly reduced. Representatives of the companies Roche and Plexxikon reported that they are going to conduct a more extensive clinical trials to determine how toxic the drug may be and what should be its optimal dose.

Both companies also hope to develop a process of testing for the diagnosis of patients with melanoma-type BRAF in the early stages of its development.